TABLE 1.
Strain | Organism | Resistance mechanism | Result with druga-inhibitor combination
|
|||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
CTT (LN)b | CTT (48)c | FOX (LN) | FOX (48) | CPD (LN) | CPD (48) | CTX (LN) | CTX (48) | CAZ (LN) | CAZ (48) | |||
HVAMC39 | K. pneumoniae | ACT-1 | Pd | Ne | N | N | P | P | P | N | N | N |
Misc304 | K. pneumoniae | MIR-1 | P | P | P | P | P | P | P | P | P | P |
Misc340 | K. pneumoniae | FOX-1 | P | N | P | P | P | P | N | N | N | N |
PAB-CM30 | E. coli | FOX-3 | P | P | P | P | P | P | P | P | P | P |
Misc416 | E. coli | FOX-4 | P | P | P | P | P | P | P | P | P | P |
CCF52 | K. pneumoniae | FOX-5 | N | P | P | N | P | P | N | N | P | P |
Kleb249 | K. pneumoniae | CMY-2 | P | P | P | P | P | P | P | P | P | P |
UMJMH14 | K. pneumoniae | DHA-1 | P | P | P | P | P | P | P | P | P | P |
CDC2085 | H. alvei | ACC-1 | N | P | N | N | P | P | P | P | P | P |
Misc339 | K. pneumoniae | MOX-1 | N | P | N | N | N | P | N | P | N | P |
Drugs tested: cefotetan (CTT), cefoxitin (FOX), cefpodoxime (CPD), cefotaxime (CTX), and ceftazidime (CAZ).
Inhibitor LN-2-128.
Inhibitor 48-1220.
P, positive test: increase of ≥4 mm in zone diameter in the presence of the inhibitor.
N, negative test: increase of ≤3 mm in zone diameter in the presence of the inhibitor.