TABLE 2.
Strain | Organism | Resistance mechanism | Result with druga-inhibitor combination
|
|||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
CTT (LN)b | CTT (48)c | FOX (LN) | FOX (48) | CPD (LN) | CPD (48) | CTX (LN) | CTX (48) | CAZ (LN) | CAZ (48) | |||
Kleb67 | K. oxytoca | Hyper K1 | Nd | N | N | N | Pe | P | P | P | N | N |
Kleb196 | K. pneumoniae | OMP | N | N | N | N | N | N | N | N | N | N |
PAB-C14 | E. coli | SHV-2 | N | N | N | N | N | P | N | P | N | P |
Kleb116 | K. pneumoniae | SHV-5 | N | N | N | N | N | P | P | P | N | P |
PAB-C3 | E. coli | TEM-3 | N | N | N | N | N | P | P | P | N | P |
PAB-C10 | E. coli | TEM-10 | N | N | N | N | N | P | N | P | N | P |
Misc337 | E. coli | CTX-M-1 | N | N | N | N | N | P | P | P | N | N |
Misc419 | E. coli | CTX-M-14 | N | N | N | N | P | P | N | P | N | N |
PAB-C19 | E. coli | OXA-2 | N | N | N | N | N | N | N | N | N | P |
Kleb265 | K. pneumoniae | KPC-1 | P | N | N | N | P | N | P | N | N | N |
Drugs tested: cefotetan (CTT), cefoxitin (FOX), cefpodoxime (CPD), cefotaxime (CTX), and ceftazidime (CAZ).
Inhibitor LN-2-128.
Inhibitor 48-1220.
N, negative test: increase of ≤3 mm in zone diameter in the presence of the inhibitor.
P, positive test: increase of ≥4 mm in zone diameter in the presence of the inhibitor.