Table 1.
Categories that were significantly enriched (p-value below 0.01) based on the physiological function of the genes whose elimination increases the susceptibility to acetic acid
| Category | p-value | Number of genes in the dataset | Number of genes in the category |
|---|---|---|---|
| Biological Process | |||
| Mitochondrial translation [GO:0032543] | 1.83E-09 | 23 | 88 |
| Translation [GO:0006412] | 4.51E-06 | 41 | 318 |
| ATP hydrolysis coupled proton transport [GO:0015991] | 3.76E-05 | 7 | 17 |
| Regulation of SNARE complex assembly [GO:0035542] | 1.97E-04 | 4 | 6 |
| Ion transport [GO:0006811] | 2.75E-04 | 17 | 107 |
| Protein N-linked glycosylation [GO:0006487] | 7.11E-04 | 8 | 33 |
| Proton transport [GO:0015992] | 7.28E-04 | 9 | 41 |
| Protein lipoylation [GO:0009249] | 9.01E-04 | 3 | 4 |
| Golgi to endosome transport [GO:0006895] | 1.12E-03 | 5 | 14 |
| Protein complex assembly [GO:0.001261] | 1.26E-03 | 7 | 28 |
| Proteolysis [GO:0006508] | 1.79E-03 | 12 | 74 |
| Mitochondrial translational initiation [GO:0070124] | 2.15E-03 | 3 | 5 |
| Positive regulation of gluconeogenesis [GO:0045722] | 2.15E-03 | 3 | 5 |
| Group I intron splicing [GO:0000372] | 2.26E-03 | 4 | 10 |
| Deoxyribonucleotide biosynthetic process [GO:0009263] | 4.10E-03 | 3 | 6 |
| Vacuolar acidification [GO:0007035] | 4.33E-03 | 6 | 26 |
| Positive regulation of mitochondrial translation [GO:0070131] | 4.82E-03 | 4 | 12 |
| tRNA aminoacylation for protein translation [GO:0006418] | 4.92E-03 | 7 | 35 |
| Regulation of vacuole fusion. non-autophagic [GO:0032889] | 6.62E-03 | 4 | 13 |
| Positive regulation of transcription from RNA polymerase II promoter [GO:0045944] | 8.37E-03 | 13 | 100 |
| Mitochondrial respiratory chain complex IV assembly [GO:0033617] | 8.83E-03 | 4 | 14 |
| Cellular Component | |||
| Mitochondrion [GO:0005739] | 2.42E-11 | 118 | 1072 |
| Mitochondrial large ribosomal subunit [GO:0005762] | 1.79E-08 | 15 | 43 |
| Mitochondrial ribosome [GO:0005761] | 3.90E-06 | 6 | 9 |
| alpha-1.6-mannosyltransferase complex [GO:0000136] | 5.07E-06 | 5 | 6 |
| CORVET complex [GO:0033263] | 5.07E-06 | 5 | 6 |
| Mitochondrial inner membrane [GO:0005743] | 1.31E-04 | 27 | 204 |
| Ribosome [GO:0005840] | 1.64E-04 | 36 | 310 |
| HOPS complex [GO:0030897] | 1.97E-04 | 4 | 6 |
| Proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178] | 4.37E-04 | 4 | 7 |
| Ribonucleoside-diphosphate reductase complex [GO:0005971] | 9.01E-04 | 3 | 4 |
| Mitochondrial matrix [GO:0005759] | 1.23E-03 | 16 | 111 |
| Large ribosomal subunit [GO:0015934] | 2.20E-03 | 5 | 16 |
| Ribonucleoprotein complex [GO:0030529] | 2.38E-03 | 32 | 307 |
| Transcriptional repressor complex [GO:0017053] | 3.83E-03 | 2 | 2 |
| Mitochondrial proton-transporting ATP synthase, catalytic core [GO:0005754] | 3.83E-03 | 2 | 2 |
| SPOTS complex (serine palmitoyltransferase) [GO:0035339] | 4.10E-03 | 3 | 6 |
| Extrinsic to mitochondrial inner membrane [GO:0031314] | 5.01E-03 | 5 | 19 |