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. 2014 Apr 26;8(5):5141–5153. doi: 10.1021/nn501197v

Scheme 2. In vitro and in vivo DNA delivery scheme.

Scheme 2

A library of PBAEs is evaluated for DNA delivery efficacy in brain tumor initiating cells (BTICs) and low efficacy in fetal neural progenitor cells (fNPCs). The top formulation was used to deliver a fluorescence gene to tumor cells in a mouse model of GBM.