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. 2014 Apr 22;8(5):4403–4414. doi: 10.1021/nn4062726

Figure 5.

Figure 5

Effects of HA–Zn0.4Fe2.6O4 NC on MSC properties. (A,B) In vitro cytotoxicity was investigated by (A) MTT assay and (B) firefly luciferase (Fluc) bioluminescence imaging after 48 h treatment with different concentrations of particles. (C) Luciferase activity of unlabeled and labeled MSC-Fluc was acquired and (D) analyzed by a Xenogen IVIS100 imaging system. The MSC-Fluc cells were untreated and treated with HA–Zn0.4Fe2.6O4 NC for 2 h, and subsequently, 5 × 104 cells were injected into brain parenchyma in a traumatic brain injury model. (E) FACS analyses of the surface markers of labeled and unlabeled MSCs after 24 h treatment.