FIG. 1.

Genetic relationships of the 293 M. tuberculosis isolates. This dendrogram was generated by using the UPGMA algorithm based on the 166 distinct MIRU-VNTR patterns (Table 1) which represented the 293 isolates. M. canettii (26) was used as an outgroup. The M. tuberculosis EAI, W/Beijing, Delhi, and Haarlem families are indicated. Group I includes only the ancestral EAI strains which were TbD1⁺, and group II includes all of the modern M. tuberculosis strains which were TbD1⁻. The allele number in locus 24 is indicated as 24:n. The linkage distance is indicated at the left bottom corner.