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. 2013 Dec 3;14(1):847. doi: 10.1186/1471-2164-14-847

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© Sibthorp et al.; licensee BioMed Central Ltd. 2013

This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Alternative splicing of A. nidulans transcripts. (A) Three examples of exon skipping/retention identified by whole transcriptome mapping and experimentally verified. (B) An extreme example of alternative splicing: a putative snoRNA cluster on chromosome V. Black boxes represent putative snoRNAs, grey boxes represent exons. Solid lines represent splicing events verified by RT-PCR. (C) Intron retention (solid lines beneath diagram) verified by RT-PCR and sequencing in the snoRNA cluster. The cluster displays a complex combination of splicing, intron retention and exon skipping.