Table 3.
Top 20 potential SUMO-1 targeting TFs after KSHV reactivation
| Rank | Name | Transfac | TFBS # (in TSS±500 bp) | Peak # of TFBS (in TSS±500 bp) | % of TFBS Peak (in TSS±500 bp) | Gene # | |||
|---|---|---|---|---|---|---|---|---|---|
| 0 h | 12 h | 0 h | 12 h | 0 h | 12 h | ||||
| 1 | ETS1 | V$CETS1P54_01 | 1587 | 341 | 262 | 21.5% | 16.5% | 294 | 229 |
| 2 | STAT4 | V$STAT4_01 | 106 | 17 | 17 | 16.0% | 16.0% | 4 | 4 |
| 3 | ELK1 | V$ELK1_02 | 1667 | 333 | 254 | 20.0% | 15.2% | 279 | 215 |
| 4 | GABPA/NRF-2 | V$NRF2_01 | 1577 | 336 | 237 | 21.3% | 15.0% | 286 | 206 |
| 5 | STAT1 | V$STAT1_03 | 282 | 50 | 41 | 17.7% | 14.5% | 48 | 39 |
| 6 | NFATC1/2/3/4 | V$NFAT_Q6 | 487 | 48 | 70 | 9.9% | 14.4% | 22 | 23 |
| 7 | STAT5A | V$STAT5A_02 | 982 | 118 | 129 | 12.0% | 13.1% | 95 | 104 |
| 8 | MYC/MAX | V$MYCMAX_02 | 580 | 90 | 76 | 15.5% | 13.1% | 68 | 55 |
| 9 | CREB1 | V$CREB_01 | 666 | 103 | 87 | 15.5% | 13.1% | 97 | 83 |
| 10 | CUTL1 | V$CDPCR1_01 | 582 | 59 | 73 | 10.1% | 12.5% | 54 | 49 |
bold: transcription factor with evidence of SUMO modification.