Table 8.
Improvements seen with Quiver
| Correction method | Starting PacBio coverage | Indels < 5 bp before Quiver | Indels < 5 bp after Quiver | Indels < 5 bp % improvement | Indels > = 5 before Quiver | Indels > = 5 after Quiver | Indels > = 5% improvement | SNPs before Quiver | SNPs after Quiver | SNPs % improvement |
|---|---|---|---|---|---|---|---|---|---|---|
| Ion | 110X | 859 | 292 | 66.01% | 3 | 2 | 33.33% | 103 | 30 | 70.87% |
| Ion | 185X | 893 | 173 | 80.63% | 4 | 1 | 75.00% | 94 | 10 | 89.36% |
| MiSeq | 110X | 149 | 73 | 51.01% | 3 | 2 | 33.33% | 117 | 2 | 98.29% |
| MiSeq | 185X | 66 | 56 | 15.15% | 2 | 1 | 50.00% | 104 | 28 | 73.08% |
| Self-correction | 110X | 1489 | 237 | 84.08% | 4 | 2 | 50.00% | 61 | 36 | 40.98% |
| Self-correction | 185X | 358 | 90 | 74.86% | 2 | 1 | 50.00% | 14 | 5 | 64.29% |