Table 1.

Description and definition of the quantification of the filamentous or granular depositions

Score (granules or threads)	Number of inclusions (High power field (HPF) with a 40× objective)
0	Less than 1 inclusion per 4 HPF
1	More than 1 inclusion per 4 HPF, up to 5 inclusions per 1 HPF
2	5-20 inclusions per 1 HPF
3	More than 20 inclusions per 1 HPF

Scoring scheme used to semiquantitatively assess the frequency and density of granular or filamentous inclusions in DAB stained paraffin sections on a LEICA DM2500 with a 40× HCX Pan Apochromat objective.