Table 4.
Manual search for genes associated with axonal regeneration processes show that they are differentially expressed in regenerative and non-regenerative stages
|
Category |
GenBank ID | Gene name |
UniGene cluster description |
log
2
FC |
|||||
|---|---|---|---|---|---|---|---|---|---|
| R1 | R2 | R6 | NR1 | NR2 | NR6 | ||||
| Axonal guidance |
BC108561 |
ngfr |
Nerve growth factor receptor |
0.21 |
-0.20 |
-0.31 |
-0.16 |
-0.05 |
1.20 |
| |
X91191 |
epha4-a |
EPH receptor A4 |
-0.25 |
-0.09 |
0.25 |
-0.42 |
-0.48 |
-1.36 |
| |
BC043626 |
epha4-b |
EPH receptor A4 |
-0.17 |
0.13 |
0.52 |
-0.51 |
-0.16 |
-1.28 |
| |
BC060745 |
epha2 |
EPH receptor A2 |
-0.42 |
0.01 |
-0.01 |
0.07 |
1.01 |
1.46 |
| |
BC077964 |
sema4b |
Sema domain, immunoglobulin domain (Ig), transmembrane domain and short cytoplasmic domain, (semaphorin) 4B |
-0.35 |
-0.01 |
0.19 |
0.08 |
0.43 |
-1.00 |
| |
BC124869 |
sema3f |
Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3 F |
0.19 |
0.30 |
0.18 |
0.29 |
1.15 |
1.64 |
| |
AF427525 |
reln |
Reelin |
-0.30 |
0.21 |
0.32 |
-0.52 |
0.26 |
-1.16 |
| Intrinsic factors |
AY116304 |
klf15 |
Krüppel-like factor 15 |
-1.49 |
-0.58 |
-0.43 |
-0.46 |
0.64 |
-0.84 |
| |
BC092147 |
klf10 |
Krüppel-like factor 10 |
-0.18 |
-0.10 |
-0.05 |
0.28 |
0.74 |
1.72 |
| |
BC054214 |
socs3 |
Suppressor of cytokine signaling 3 |
2.12 |
2.00 |
1.72 |
2.15 |
3.72 |
4.62 |
| |
BC068752 |
socs3 |
Suppressor of cytokine signaling 3 |
3.31 |
2.05 |
1.01 |
3.40 |
4.45 |
6.55 |
| |
BC044717 |
stat3.2 |
Signal transducer and activator of transcription 3 (acute-phase response factor), gene 2 |
0.74 |
0.61 |
0.19 |
0.55 |
0.98 |
2.10 |
| BC086272 | stat6 | Signal transducer and activator of transcription 6, interleukin-4 induced | -0.43 | 0.72 | 0.47 | 0.38 | 0.57 | 1.62 | |
Two categories are shown: genes related to axonal guidance and genes associated with intrinsic factors involved in axonal regeneration. FC, fold change (transected/sham).