Table 2.
Synthesis of findings relating GWG to infant and maternal outcomes based on significance testing
| Study | n | Fetal growth | Gestational age | Optimal neonatal outcome | GDM | Gest HTN |
|---|---|---|---|---|---|---|
| Bohni et al. 2011 (20) | 173 | + | ||||
| Brown & Schloesser 1990 (21) | 503 | UW: + NL: + OV: null OB: + Sev OB: null |
||||
| Chu & D’Angelo 2009 (22) | 6345 | UW: + NL: + OV: + OB: + |
||||
| Eller et al. 1993 (24) | 80 | + | ||||
| Fox et al. 2010 (26) | 297 | NL: generally + OV: null OB: null |
NL: generally null OV: − OB: null |
NL: null OV: null OB: null |
NL: null OV: null OB: null |
|
| Fox et al. 2011 (27) | 170 | + NL: + |
null NL: null |
null NL: null |
||
| Gónzalez-Quintero et al. 2012 (28) | 5123 | NL: + OV: + OB: + |
NL: + OV: + OB: + |
NL: − OV: null OB: null |
NL: + OV: + OB: null |
|
| Lantz et al. 1996 (30) | 189 | UW: + NL: generally + OV: null |
||||
| Luke & Leurgans 1996 (36) | 924 | + | ||||
| Luke et al. 1993a (38) | 163 | + | + | + | ||
| Luke et al. 1993b (35) | 222 | + | ||||
| Luke et al. 1998 (37) | 1564 | + | ||||
| Luke et al. 2003 (33) | 2324 | ** | ||||
| Luke et al. 2004 (32) | 218 | + | ||||
| Schwendemann et al. 2005 (42) | 11,827 | + |
**
Data not provided to determine relationship
+, −, or null indicates a positive, negative, or null associations, respectively, between GWG and the outcome.
GDM, gestational diabetes; Gest HTN, gestational hypertension; UW, underweight; NL, normal weight; OB, obese; OV, overweight