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Representative photomicrographs of the H&E stained renal tissue (20X) in a sham-operated control (A) and a 5/6 nephrectomized rat (CKD)] treated with vehicle (B) or RTA dh404 (C). The remnant kidney in the CKD animals (B) exhibited significant glomerulosclerosis, tubulo-interstitial injury and heavy inflammatory cell infiltration. RTA dh404 treatment-reduced inflammatory cell infiltration and glomerular and tubulo-interstitial injury (C).
