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. 2014 May 3;10(5):530–542. doi: 10.7150/ijbs.8450

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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AGT mRNA localization in the kidney cortex proximal tubule segment (S)s of patients with diabetes. Little AGT mRNA was detected in S1 in control subjects (A) and in patients with diabetes (B). AGT mRNA in S2 did not differ significantly (E) between control subjects (C) and patients with type 2 diabetes (D). Data are presented as a fold-increase compared with the levels of control subjects. Green; AGT mRNA, Red; segment-specific marker. Dotted lines indicate the edge of glomeruli. Magnification, x200 (scale bar, 100 μm). AGT: angiotensinogen; DN: diabetic nephropathy; G: glomeruli.