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. 2014 May 3;10(5):530–542. doi: 10.7150/ijbs.8450

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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AGT protein localization in the kidney cortex proximal tubule segment (S)s of patients with diabetes. AGT protein expression in S1 was significantly greater (C) in patients with type 2 diabetes (B) compared with control subjects (A). AGT protein expression in S2 did not differ significantly (F) between and control subjects (D) and patients with type 2 diabetes (E). Data are presented as a fold-increase compared with the levels of control subjects. * P < 0.05 vs. control subjects. Green; AGT protein, Red; segment-specific marker. Magnification, x200 (scale bar, 100 μm). AGT: angiotensinogen; DN: diabetic nephropathy.