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. 2014 May 14;10(5):550–565. doi: 10.7150/ijbs.9028

Table 1.

Quorum sensing signaling molecules and phenotypes controlled in Gram-negative and Gram-positive bacteria.

Autoinducer(s) Producing bacteria Phenotype(s) controlled Ref.
Gram-negative bacteria
N-acyl homoserine lactone (AHL) V. fischeri, P. aeruginosa, C. violaceum, Aer. hydrophila Bioluminescence, Exopolysaccharide production, Biofilm formation, Virulence factor, Pigmentation 30-35
Autoinducer-2 (AI-2) V. harveyi, E. coli, Y. pestis Bioluminescence, Biofilm formation, Motility, Virulence factor 36-39
4,5-dihydroxy-2,3-pentanedione Sa. enteric serovar typhimurium Virulence factor 40, 41
Cyclic dipeptides/ Diketopiperazines (DKP)
(a) Cyclo(L-Pro-L-Tyr)
P. putida WCS358, P. aeruginosa Cross activates QS biosensors 42, 43
(b) Cyclo(L-Phe-L-Pro) P. putida WCS358, P. aeruginosa Cross activates QS biosensors 42, 43
(c) Cyclo(L-Leu-L-Pro) P. putida WCS358 Cross activates QS biosensors 42
(d) Cyclo(L-Leu-L-Val) P. putida WCS358 Cross activates QS biosensors 42
Quinolone
(2-heptyl-3-hydroxy-4-quinolone)
P. aeruginosa Antibiotic production 44-46
Diffusible factor (DSF) X. campestris Endoglucanase production 47
Gram-positive bacteria
Autoinducing peptide (AIP1-AIP4) Sta. aureus Cross-signaling between strains and species, Biofilm formation, Virulence factor 28, 29, 48, 49