Figure 5. AK4 Controls ATP Levels, Proliferation, and Expression Levels Correlate with Glioma Patient Survival.
(A), (B) Relative ATP/cell was measured in cells transfected with control or AK4 siRNAs (n=3 for each siRNA). Error bars represent SD values. **p < 0.01. Western blot depicting level of AK4 knockdown.
(C) Cell proliferation was measured by xCELLigence RTCA. Cell density measurements were taken every hour for 96 hours (n=6 for each siRNA). Error bars represent SD values.
(D) The Rembrandt database was used to perform a Kaplan-Meier survival analysis of glioma patients with differential AK4 expression and copy number.
