Fig. 1.
The effect of treatment with sex hormones on the mRNA expression of genes involved in n-3 PUFA biosynthesis in HepG2 cells. Values are mean ± SD (n = 10 replicates per treatment). Statistical analysis was by 1-way ANOVA with Dunnett’s post hoc test. * P<0.01; **P<0.001; ***P<0.0001 compared to untreated cells. ANOVA probability for the effect of progesterone treatment was for FADS1 and 2 P<0.0001, ELOVL 5 P=0.008 and ELOVL 2 P = 0.09). There were no statistically significant effects of treatment with EE2 or testosterone on the mRNA expression of any of the genes measured.
