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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Prostaglandins Leukot Essent Fatty Acids. 2013 Dec 18;90(0):47–54. doi: 10.1016/j.plefa.2013.12.006

Fig. 2.

Fig. 2

The effect of treatment with sex hormones on the mRNA expression of genes involved in n-3 PUFA biosynthesis in primary human hepatocytes. Values are mean ± SD (n = 10 replicates per treatment). Statistical analysis was by Student’s unpaired t-test. * P<0.01; **P<0.001; ***P<0.0001 compared to untreated cells. There was a statistically significant effect of progesterone treatment on FADS2 mRNA expression (P = 0.01) and a non-significant trend towards an effect of progesterone on FADS1 expression (P = 0.08). There were no statistically significant effects of treatment with progesterone on ELOVL 5 or 2 expression or of EE2 or testosterone on the expression of any of the genes measured.