Skip to main content
. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Cancer Prev Res (Phila). 2014 Jan 21;7(4):407–417. doi: 10.1158/1940-6207.CAPR-13-0304

Figure 2. Bioinformatic analyses suggest that PI3K/AKT signaling may be a key downstream pathway of tazarotene signaling.

Figure 2

Bioinformatic network analysis of the tazarotene-treated 10 h DE genes suggested that a significant number of the DE genes connected to the PI3K/AKT pathway as a central downstream node. The shaded shapes indicated the DE genes (* p < 0.05). The different shapes assigned to each molecule that was represented in the 10 h DE list, indicate the type/function of the protein as classified by the IPA analysis software (Ingenuity®, CA).