Figure 1. Humoral response against ribosomal P proteins and their C-terminal peptides.

The presence of antibodies directed against P2β and CP0 proteins as well as peptides R13, P015 and H13 in the sera of 27 patients with chronic Chagas' disease Cardiomyopathy patients (CCC) and 20 non-infected individuals (NI) was determined by ELISA as described under Methods. Results are expressed as Reactivity index, calculated as: (Optical Density mean value obtained of each serum sample/baseline value). Each symbol represents data from a single subject. Statistical analysis was performed using the Mann-Whitney U Test, ***P<0.001, *P<0.05. The line for each of the scatters represents the median.