Table 2. Anthropometric data, UGT1A1*28 polymorphism, haematological and biochemical parameters of obese patients according to body fat percentage (n = 74) lower or higher/equal than 42.5% (median value for the obese group).
| Obese patients (n = 74) | |||
| Body fat ≤42.5% | Body fat >42.5% | p | |
| Number of participants | 37 | 37 | |
| Female, n (%) | 13 (35.1%) | 21 (56.8%) | 0.102 |
| Age (years) | 11.0±3.0 | 9.5±2.5 | 0.022 |
| Height (cm) | 149.2±14.3 | 144.0±14.2 | 0.126 |
| Weight (kg) | 59.8±18.9 | 61.4±23.9 | 0.749 |
| BMI (kg/m2) | 26.0±4.0 | 28.4±5.5 | 0.041 |
| BMI z-score | 1.98±0.24 | 2.31±0.26 | <0.001 |
| Body fat (%) | 36.8±4.3 | 46.1±2.6 | <0.001 |
| Trunk fat (%) | 34.5±5.5 | 45.3±3.4 | <0.001 |
| UGT1A1 genotype | |||
| 6/6, n (%) | 21 (56.8%) | 19 (51.4%) | 0.359 |
| 6/7, n (%) | 14 (37.8%) | 18 (48.6%) | |
| 7/7, n (%) | 2 (5.4%) | 0 (0%) | |
| RBC (×1012/L) | 4.83±0.38 | 4.91±0.34 | 0.389 |
| Hb (g/dL) | 13.9±1.0 | 13.6±0.8 | 0.268 |
| Ht (L/L) | 0.41±0.03 | 0.41±0.02 | 0.798 |
| MCV (fL) | 85.4±4.9 | 83.8±4.6 | 0.156 |
| MCH (pg) | 28.7±1.7 | 27.8±1.5 | 0.017 |
| MCHC (g/dL) | 33.6±0.8 | 33.2±0.9 | 0.020 |
| Total bilirubin (µmol/l) | 11.29 (8.72–14.36) | 8.89 (7.69–11.63) | 0.013 |
| Acute phase protein | |||
| CRP (mg/L) | 1.31 (0.84–2.30) | 2.00 (1.43–3.54) | 0.017 |
| Glucose metabolism | |||
| Glucose (mg/dl) | 83.5±7.6 | 81.0±8.6 | 0.191 |
| Insulin (µU/ml) | 11.6 (8.9–14.6) | 15.3 (7.5–22.9) | 0.272 |
| HOMAIR | 2.25 (1.91–3.01) | 3.15 (1.57–4.56) | 0.361 |
Values are given as mean ± SD or median (interquartile range), unless otherwise indicated.
BMI, body mass index; RBC, red blood cells; Hb, haemoglobin; Ht, haematocrit; MCV, mean cell volume; MCH, mean cell haemoglobin; MCHC, mean cell haemoglobin concentration; CRP, C-reactive protein; HOMAIR, homeostasis model assessment insulin resistance.