Table 2.
Biochemical parameters and echocardiogram findings
| Group I N = 13 | Group II N = 15 | Group III N = 81 | Group IV N = 45 | Group V N = 30 | P | |
|---|---|---|---|---|---|---|
| GFR (mL/min) |
106.8 ± 9.2 |
69.2 ± 6.1 |
42.9 ± 9.4 |
24.7 ± 7.5 |
10.9 ± 3.4 |
0.013 |
| Creatinine (mg/dL) |
64.1 ± 20.1 |
103.0 ± 19.4 |
126.6 ± 40.5 |
331.4 ± 148.4 |
497.3 ± 377.9 |
0.003 |
| Troponin T (ng/mL) |
0.12 ± 0.10 |
0.09 ± 0.04 |
0.41 ± 0.33 |
0.21 ± 0.09 |
0.59 ± 0.49 |
0.918 |
| CK-MB (U/L) |
7.3 ± 2.9 |
9.9 ± 3.6 |
13.1 ± 4.6 |
13.2 ± 3.7 |
17.2 ± 9.7 |
0.627 |
| Hgb (g/dL) |
123.1 ± 12.1 |
135.8 ± 13.9 |
127.6 ± 18.2 |
107.1 ± 23.7 |
93.2 ± 22.9 |
0.000 |
| TC (mmol/L) |
3.6 ± 1.2 |
5.3 ± 1.6 |
4.3 ± 1.1 |
4.4 ± 1.6 |
3.4 ± 0.9 |
0.159 |
| LDL-C (mmol/L) |
2.3 ± 0.9 |
2.9 ± 1.2 |
2.4 ± 0.7 |
2.5 ± 1.3 |
1.8 ± 0.6 |
0.257 |
| hs-CRP (mg/dL) |
0.6 ± 0.5 |
1.1 ± 0.7 |
1.7 ± 0.9 |
2.7 ± 1.2 |
4.9 ± 3.7 |
0.000 |
| Cys C (mg/l) |
0.6 ± 0.3 |
1.0 ± 0.4 |
1.4 ± 0.5 |
2.4 ± 1.2 |
3.7 ± 2.8 |
0.000 |
| NT-proBNP (pg/mL) |
307.6 ± 52.4 |
1013.8 ± 639.5 |
4305.5 ± 1054.5 |
9687.3 ± 3014.7 |
10636.8 ± 4016.9 |
0.000 |
| LVEF (%) |
62 ± 13 |
53 ± 13 |
48 ± 11 |
49 ± 10 |
46 ± 12 |
0.007 |
| IVS (mm) |
9.3 ± 1.5 |
10.8 ± 1.8 |
11.2 ± 1.3 |
11.9 ± 1.4 |
12.2 ± 1.8 |
0.021 |
| LVPWT (mm) |
9.3 ± 1.4 |
11.4 ± 2.3 |
10.6 ± 1.2 |
11.2 ± 1.7 |
12.0 ± 1.1 |
0.028 |
| EDV (ml) | 48.0 ± 3.0 | 48.8 ± 6.2 | 49.4 ± 5.9 | 50.5 ± 6.8 | 56.2 ± 5.6 | 0.046 |
GFR, glomerular filtration rate; Hgb, hemoglobin; TC, total cholesterol; LDL, low-density lipoprotein; hs-CRP, high-sensitivity C-reactive protein; NT-proBNP, N-terminal pro-B-type natriuretic peptide; CK-MB, creatine kinase-MB; NS, not significant; Cys C, cystatin C; LVEF, left ventricular ejection fraction; IVS, interventricular septal thickness; LVPWT, left ventricular posterior wall thickness; EDV, left ventricular end-diastolic inner volume.