Table 2. Clinical correlates of HIV transmission.
| Baseline parameter | Putative transmission* | Analysis | |||
| Yes | No | Univariate | Multivariate | ||
| Plasma VL (median log10 RNA copies/mL) | 5.2 | 4.7 | p<0.01 | OR = 2.0, P<0.01 | |
| CD4 count (median cells/µl) | 382 | 469 | p = 0.53 | ||
| Number of sex partners (median previous month) | 3.0 | 1.5 | p = 0.03 | OR = 1.8†, P = 0.03 | |
| UAI, receptive | Any | 76.0% | 64.8% | p = 0.34 | |
| None | 24.0% | 35.2% | |||
| UAI, insertive | Any | 69.2% | 60.4% | p = 0.50 | |
| None | 30.8% | 39.6% | |||
| Race | White | 75.9% | 50.4% | p = 0.02 | |
| Hispanic | 20.7% | 28.1% | |||
| Other | 3.5% | 21.5% | |||
| Stage of infection | Acute/Early | 72.1% | 64.1% | p = 0.52 | |
| Established | 27.6% | 35.9% | |||
| TNS (>0.75) | 44.8% | 15.6% | <0.01 | OR = 4.0, P<0.01 | |
UAI = unprotected anal intercourse, VL = viral load.
*Defined as ≥1 acquired outbound network connection(s) in the first year after incident HIV infection.
†
The log-transformed number of sex partners was used in the regression model, so OR = 1.8 corresponds to the odds of transmission for subjects with 1 sex partner compared to subjects with 0 sex partners (OR = 1.4 when comparing 2 to 1 sex partners).