Skip to main content
. 2014 Jun 5;9(6):e98458. doi: 10.1371/journal.pone.0098458

Figure 4. Influence of progastrin on human M1 and M2 macrophages.

Figure 4

Human monocyte-derived macrophages were stimulated with LPS plus IFNγ to obtain a M1-phenotype or with IL4 to obtain M2-macrophages in the presence or absence of progastrin, and the resultant phenotype evaluated by analyzing the following parameters: expression of CD86 (A, n = 3); expression of CD206 (B, n = 5); secretion of IL10 (C, D, n = 5); and secretion of IL12 (E, F, n = 5). Bars represent mean ±SEM. *P<0.05 vs corresponding value in vehicle-treated cells; + P<0.05 and ++P<0.01 vs corresponding value in control cells.