Skip to main content
. Author manuscript; available in PMC: 2014 Jul 23.
Published in final edited form as: Nature. 2014 Jan 23;505(7484):509–514. doi: 10.1038/nature12940

Figure 4.

Figure 4

Distinct regions of caspase-1 and caspase-3 activity in lymph node of a patient chronically infected with R5-tropic HIV. Inguinal lymph node was collected from a 50-year-old immunosuppressed HIV-1 infected subject during the chronic phase of disease. The patient was first identified with HIV in 1985, has not been on anti-retroviral therapy and displayed CD4 count of 156 cells/μl and viral load of 85,756 copies/ml at the time of lymph node resection. (See also Extended Data Figure 8). GC, germinal center; MZ, mantle zone; PC, paracortical zone; E, epithelium.