Table 4.
Association Between Preoperative Iris Thickness and Changes in Anterior Segment Biometric Parameters After Laser Peripheral Iridotomy in Primary Angle Closure Suspects (Caucasian Subjects)
| Outcome | Predictor | P Values of Univariate Regression Model | Regression Coefficients (95% CI) | P Values of Multivariate Linear Regression Modela | Regression Coefficients (95% CI) |
|---|---|---|---|---|---|
| Δ ICURV (mm) | Preoperative IT750 (mm) | 0.142 | −0.355 (−0.113, 0.880) | 0.157 | 0.385 (−0.131, 0.901) |
| Preoperative IT2000 (mm) | <0.0001 | 0.928 (0.566, 1.290) | <0.0001 | 0.887 (0.518, 1.256) | |
| Preoperative ITM (mm) | 0.009 | 0.668 (0.199, 1.137) | 0.012 | 0.682 (0.185, 1.179) | |
| Δ TISA500 (mm2) | Preoperative IT750 (mm) | 0.005 | −0.186 (−0.308, −0.064) | 0.013 | −0.179 (−0.310, −0.048) |
| Preoperative IT2000 (mm) | 0.085 | −0.119 (−0.250, 0.011) | 0.075 | −0.127 (−0.261, 0.006) | |
| Preoperative ITM (mm) | 0.128 | −0.111 (−0.251, 0.027) | 0.155 | −0.113 (−0.265, 0.038) | |
| Δ TISA750 (mm2) | Preoperative IT750 (mm) | 0.017 | −0.302 (−0.536, −0.069) | 0.031 | −0.285 (−0.528, −0.042) |
| Preoperative IT2000 (mm) | 0.047 | −0.251 (−0.488, −0.014) | 0.038 | −0.263 (−0.498, −0.028) | |
| Preoperative ITM (mm) | 0.158 | −0.191 (−0.450, 0.067) | 0.163 | −0.199 (−0.472, 0.072) |
a
Adjusted for age, sex, and preoperative pupil diameter.
ICURV = iris curvature, TISA500 = trabecular–iris space area at 500 μm from the scleral spur, TISA750 = trabecular–iris space area at 750 μm from the scleral spur, IT750 = iris thickness measured at 750 μm from the scleral spur, IT2000 = iris thickness measured at 2000 μm from the scleral spur, ITM = maximal iris thickness, CI = confidence interval