Table 5.
Discrimination Measures for Three Methods of adding a novel biomarker for predicting AF risk
Model | CRP | BNP | ||||
---|---|---|---|---|---|---|
Method 1 n=3120 |
Method 2 n=3120 |
Method 3 n=3120 |
Method 1 n=3120 |
Method 2 n=3120 |
Method 3 n=3120 |
|
C before adding biomarker | 0.7789 | 0.7789 | 0.7535 | 0.7789 | 0.7789 | 0.7535 |
C after adding biomarker | 0.7832 | 0.7826 | 0.7657 | 0.8032 | 0.8020 | 0.7977 |
Difference in C-statistic | 0.0043 | 0.0035 | 0.0122 | 0.0243 | 0.0231 | 0.0442 |
P-value for difference | 0.2184 | 0.2777 | 0.0225 | 0.0018 | 0.0015 | 0.00003 |
NRI | 0.1690 | 0.2148 | 0.2572 | 0.4244 | 0.3581 | 0.4506 |
IDI | 0.0025 | 0.0018 | 0.0035 | 0.0172 | 0.0161 | 0.0249 |