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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Genes Immun. 2014 Feb 27;15(4):218–223. doi: 10.1038/gene.2014.7

Figure 1.

Figure 1

(a) The 1:1 and the exhaustive matching strategies for a case-parents trio at two loci. Tf: the allele transmitted to the child by the father. Nf: the allele not transmitted to the child by the father. Tm: the allele transmitted to the child by the mother. Nm: the allele not transmitted to the child by the mother. H1: all possible offspring genotypes given the couple's genotypes under the 1:1 matching. HE: all possible offspring genotypes given the couple's genotypes under the exhaustive matching. Under the null hypothesis of no association, the two genotypes in H1 are equally likely; under the null hypothesis of no association and linkage equilibrium between the two SNPs, the 16 genotypes in HE are equally likely. (b) The matching strategy used to analyze the four SNPs in this study.