Figure 5.
Inhibition of glucose transport by compound 5. H1299 human lung cancer cells were treated by vehicle, WZB117 (30 µM, positive control), or 5 (30 µM) for 15 min. After glucose uptake was initiated by 2-deoxy-d-[3H] glucose, cells were lysed and the radioactivity of the cell lysates was measured. The result showed that compound 5 inhibited glucose transport (columns, means, n = 3; bars, SE; ** p ≤ 0.01 and *** p ≤ 0.001).