Table 3.

Median (Interquartile Range) of Pupil Response Parameters to the Full-Field White Stimulus with Pooled Area under the Receiver Operating Characteristic Curves for Sample Mean Age of 60.9 Years and True-Positive Rates at Fixed False-Positive Rates

Full-Field White Stimulus	Glaucoma Subjects (n = 66)	Healthy Subjects (n = 50)	P Value*	Area under the Receiver Operating Characteristic Curve (Standard Error)	True-Positive Rate
					False-Positive Rate, 0.05	False-Positive Rate, 0.2
RespAmpR	0.28 (0.24–0.32)	0.30 (0.28–0.32)	0.001	0.60 (0.05)	0.14	0.47
RespAmpL	0.28 (0.24–0.31)	0.30 (0.27–0.32)	<0.001	0.59 (0.05)	0.10	0.38
RespLatR	183 (168–205)	168 (159–178)	<0.001	0.59 (0.06)	0.10	0.41
RespLatL	183 (169–199)	168 (161–180)	<0.001	0.57 (0.05)	0.14	0.38
ConMaxVelR	4.2 (3.6–5.0)	5.1 (4.1–6.1)	<0.001	0.54 (0.07)	0.10	0.24
ConMaxVelL	4.1 (3.6–5.0)	5.1 (4.2–5.9)	<0.001	0.51 (0.07)	0.12	0.20
ConMaxVelLatR	397 (374–421)	375 (366–393)	<0.001	0.59 (0.06)	0.11	0.39
ConMaxVelLatL	398 (385–417)	381 (369–390)	<0.001	0.65 (0.05)	0.06	0.52
DilMaxVelR	2.4 (2.0–2.7)	2.7 (2.3–3.1)	<0.001	0.53 (0.07)	0.08	0.23
DilMaxVelL	2.5 (2.1–2.7)	2.8 (2.4–3.1)	<0.001	0.54 (0.08)	0.08	0.14
DilMaxVelLatR	1121 (1075–1175)	1110 (1056–1141)	0.018	0.52 (0.05)	0.08	0.23
DilMaxVelLatL	1120 (1075–1173)	1101 (1066–1130)	0.006	0.54 (0.04)	0.14	0.29
absRAPDscore	0.17 (0.06–0.30)	0.09 (0.04–0.15)	<0.001	0.60 (0.05)	0.20	0.42

The best performing parameters are shown in bold.

absRAPDscore = absolute relative afferent pupillary defect score; ConMaxVel = maximum velocity of constriction; ConMaxVelLat = latency of the maximum velocity of constriction; DilMaxVel = maximum velocity of dilation; DilMaxVelLat = latency of the maximum velocity of dilation; L = left; R = right; RespAmp = response amplitude; RespLat = response latency.

^*Wilcoxon signed-rank test.