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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Leukemia. 2013 Dec 5;28(6):1242–1251. doi: 10.1038/leu.2013.368

Figure 7.

Figure 7

Overexpression of Myc in primary mouse hematopoietic progenitors results in elevated DSBs. (A) Murine c-kit+ enriched cells were transduced with MSCV-Ires-GFP control virus or MSCV-Myc-Ires-GFP and virally transduced cells were sort purified (GFP+/propidium iodide negative) after 3 days. DNA was subjected to the neutral Comet assay. The experiment was repeated 2 times, and 100 Comets were scored for each experiment. Box-whisker plots were generated as previously described in Figure 4. (B) Representative Comets from c-kit+ enriched cells transduced with control virus (MSCV) and the Myc overexpressing virus (MSCV-Myc) are shown.