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Pharmacokinetic properties of VN/14-1 (oral vs intravenous)
| Route Dose | Cmax (mg/ml) | tmax (h) | t1/2 (h) | AUC (0-∞) (h*mg/ml) | Bioavailability |
|---|---|---|---|---|---|
| Oral (20 mg/kg) | 38.2 | 0.50 | 1.41 | 93.9 | 1.34 |
| Intravenous (20 mg/kg) | 107 | - | 0.98 | 70.3 |
Pharmacokinetic parameters of VN/14-1 in female rats after oral or i.v. dose of 20 mg/kg. Cmax maximum plasma concentration, tmax time taken to achieve Cmax, t1/2 elimination half-life, AUC area under the curve.
