Table 1.
Clinical characteristics in elderly and younger hepatitis B virus-related hepatocellular carcinoma patients n (%)
| Clinical characteristics | Elderly (≥ 65 yr) (n = 207) | Younger (< 65 yr) (n = 1336) | P value |
| Age (yr), median (IQR) | 68 (66-73) | 47 (40-56) | < 0.001 |
| Male | 166 (80.2) | 1128 (84.4) | 0.123 |
| Body mass index (kg/m2), mean (SD) | 22.8 (2.9) | 22.9 (2.9) | 0.899 |
| HBsAg(+) | 123 (59.4) | 1127 (84.4) | < 0.001 |
| HBeAg(+) | 10 (4.8) | 236 (17.7) | < 0.001 |
| HBV DNA (+) | 50 (24.2) | 433 (32.4) | 0.017 |
| AST (U/L), median (IQR) | 35 (25-55) | 40 (29-64) | 0.001 |
| ALT (U/L), median (IQR) | 34 (24-49) | 40 (29-60) | < 0.001 |
| White Blood Cells (109/L), median (IQR) | 5.34 (4.18-6.67) | 5.37 (4.25-6.63) | 0.656 |
| Hemoglobin (g/L), median (IQR) | 134 (122-144) | 143 (130-153) | < 0.001 |
| Platelets (109/L), median (IQR) | 136 (92-185) | 130 (92-183) | 0.999 |
| Portal hypertension | 52 (25.1) | 376 (28.1) | 0.366 |
HCC: Hepatocellular carcinoma; HBV: Hepatitis B virus; HBsAg: Hepatitis B surface antigen; HBeAg: Hepatitis B e antigen; HBV-DNA: Positive indicated by hepatitis B virus DNA > 2000U/mL; IQR: Interquartile range; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase.