Table 1.
SNP | Ref. | Year | Country | Ethnicity |
AP |
Control |
P value for HWE | Source of controls | AP | Control | Assay | ||||
AA | AB | BB | AA | AB | BB | ||||||||||
Asp299Gly | Hofner et al[11] | 2006 | Hungary | Caucasian | 84 | 7 | 1 | 64 | 7 | 2 | 0.01 | PB | 92 | 73 | Taqman |
Gao et al[10] | 2007 | China | Asian | 101 | 22 | 0 | 71 | 9 | 0 | 0.59 | PB | 123 | 80 | PCR-RFLP | |
Zhang et al[9] | 2008 | China | Asian | 238 | 0 | 0 | 121 | 0 | 0 | 1.00 | PB | 238 | 121 | PCR-RFLP | |
Takagi et al[8] | 2009 | Japan | Asian | 202 | 0 | 0 | 286 | 0 | 0 | 1.00 | PB | 202 | 286 | PCR-RFLP | |
Chen et al[12] | 2009 | China | Asian | 64 | 15 | 0 | 47 | 6 | 0 | 0.76 | PB | 79 | 53 | PCR-RFLP | |
Guenther et al[7] | 2010 | Germany, United States | Caucasian | A 991 G 51 | A 725 G 45 | PB | 521 | 385 | Taqman | ||||||
Thr399Ile | Hofner et al[11] | 2006 | Hungary | Caucasian | 85 | 6 | 1 | 64 | 7 | 2 | 0.01 | PB | 92 | 73 | Taqman |
Takagi et al[8] | 2009 | Japan | Asian | 202 | 0 | 0 | 286 | 0 | 0 | 1.00 | PB | 202 | 286 | PCR-RFLP | |
Guenther et al[7] | 2010 | Germany, United States | Caucasian | C 977 T49 | C 728 T 36 | PB | 521 | 385 | Taqman |
SNP: Single nucleotide polymorphisms; AP: Acute pancreatitis; PB: Population-based study; HWE: Hardy-Weinberg equilibrium in controls; PCR-RFLP: Polymerase chain reaction-restriction fragment length polymorphism.