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. 2014 Apr 22;289(23):15957–15967. doi: 10.1074/jbc.M114.562686

TABLE 1.

Conservation patterns of the orthologs of the MVA pathway-related enzymes

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* The proteins of COG2605 have been predicted to be MVK without biochemical evidence.

** The modified MVA pathway used by most archaea (and possibly by some bacteria of phylum Bacteroides (3)) is considered to be identical with the Roseiflexus/Haloferax-type MVA pathway, although the enzyme corresponding to PMD has yet to be identified.