FIGURE 7.
α-N-methylation of DDB2 stimulates CPD repair in human cells. a, flow cytometry results showing the level of CPD in GM01389 with empty control, wild-type DDB2, and DDB2-K4Q at various time intervals (0, 12, 24, and 48 h) after irradiation with 10 J/m2 UV-C light. b, quantitative results showing that CPD was repaired more efficiently in GM01389 cells with transient expression of wild-type DDB2 than in those with DDB2-K4Q. The results represent the mean ± S.E. of data obtained from three biological replicates. ***, p < 0.001. The p values were calculated by unpaired, two-tailed Student's t test.