TABLE 1.
Cytokine expression in GKO/KPC and KPC pancreatic tumor
Pancreatic tumors/tissues were analyzed by qPCR. FAS and FASL expression levels are significantly decreased in GKO/KPC mice
| Cytokine (2ΔCp) | GKO/KPC n = 4 |
KPC n = 4 |
p value | ||
|---|---|---|---|---|---|
| Mean | S.E. | Mean | S.E. | ||
| FAS (CD95) | 1.54 | 0.5 | 21.17 | 3.2 | *0.008 |
| FASL (CD95L) | 0.99 | 0.7 | 18.55 | 3.9 | *0.010 |
| IL-1b | 151.50 | 90.8 | 114.30 | 50.2 | 0.736 |
| IL-2 | 8.280 | 6.187 | 302.74 | 174.8 | 0.191 |
| IL-6 | 32.01 | 19.1 | 6.11 | 2.6 | 0.343 |
| IL-8 | 19.61 | 30.8 | 24.46 | 9.7 | 0.829 |
| IL-12p40 | 3.78 | 3.6 | 2.98 | 1.6 | 0.657 |
| IL-17 | 1.25 | 1.1 | 3.87 | 1.9 | 0.171 |
| IL-22 | 3.79 | 2.3 | 8.11 | 5.3 | 0.914 |
| INFγ | 3.14 | 2.1 | 6.17 | 2.3 | 0.343 |
| MCP-1 | 756.5 | 160.0 | 1008.00 | 374.8 | 0.570 |
| TGFβ | 13.54 | 9.7 | 7.52 | 2.8 | 0.587 |
| TNFα | 92.36 | 38.0 | 79.66 | 15.0 | 0.772 |
| TSLP | 15.11 | 6.2 | 14.57 | 2.29 | 0.939 |