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. 2014 Apr 1;13(6):1552–1562. doi: 10.1074/mcp.M113.031203

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© 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

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Fig. 8. — Comparison of protein-centric and splice-centric quantitative analysis in the stem cell dataset. A, comparison of Fibro/hiPS protein ratios determined via protein-centric analysis and splice-variant-centric analysis on proteins with splice variants identified. 296 proteins with splice variants identified in both MS experiments (biological replicates) were included. The Fibro/hiPS ratio in the figure was calculated as the mean of the two replicates. The red dots indicate proteins that showed differences in log2(Fibro/hiPS) values greater than 0.5 (1.41-fold) between protein-centric and splice-variant-centric analyses. B, zoomed view of the top 10 proteins ranked according to differences in log2(Fibro/hiPS) between protein-centric and splice-variant-centric quantification.