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Effect of rhIGF-I +/− OCP on BMD. Administration of recombinant human insulin like growth factor-I (IGF-I) (30 mcg/kg b.i.d. subcutaneously) increased bone density in adult women with anorexia nervosa. The effect was most marked when IGF-I was given with a birth control pill (Reprinted with permission from the Journal of Clinical Endocrinology and Metabolism, 2002;87:2888. Copyright © 1999 The Endocrine Society. All rights reserved)
