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. Author manuscript; available in PMC: 2014 Jun 6.
Published in final edited form as: Ultrasonics. 2013 Jul 11;54(1):177–186. doi: 10.1016/j.ultras.2013.06.008

Table 2.

Multiple regressions showed several inflammatory factors were correlated to the increases of echogenicity in the mice after tibia fracture (*, p < .05). The contribution of different candidate variables in echogenicity was examined by the backward elimination of each variable or combinations. The adjusted R-square (Adj. R2) suggested the best combination to reflect the hyperechogenic ultrasonography in fractured bone was the positive cells in TUNEL and COX-2 immunostaining (underline Adj. R2 = 0.963).

Contribution variables Deleted factor Adj. R2 P value
TUNEL + COX-2 + BLT1 0.959 <0.01*
TUNEL + COX-2 BLT1 0.963 <0.01*
TUNEL + BLT1 COX-2 0.268 0.099
COX-2 + BLT1 TUNEL 0.959 <0.01*
TUNEL BLT1, COX-2 0.335 0.029*
COX-2 BLT1, TUNEL 0.954 <0.01*
BLT1 COX-2, TUNEL 0.289 0.041*