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Comparison of T. cruzi-specific T-cell responses by country stratified by Chagatek serologic status. PBMCs were stimulated with media alone or T. cruzi antigen (Tc21 strain) in an ELISPOT assay as described. Data are expressed as IFNγ SFUs induced by T. cruzi antigen. Data are displayed as a box and whiskers graph, with minimum and maximum values shown. (A) IFNγ responses from SN or SP individuals in Peru and Bolivia. (B) SFUs of only IFNγ responders.
