Table 1.
The predicted top ten combinations of drugs for the treatment of type 2 diabetes
| Drug 1 | Drug 2 | m1 | n1 | m2 | n2 | Score |
|---|---|---|---|---|---|---|
| Trifluridine |
Trolox C |
22 |
8 |
61 |
24 |
518 |
| Thiethylperazine |
Trolox C |
17 |
6 |
63 |
17 |
506 |
| Cytisine |
Trolox C |
15 |
6 |
60 |
8 |
468 |
| Cytisine |
Ozagrel |
23 |
8 |
48 |
20 |
420 |
| Prenylamine |
Thiethylperazine |
17 |
1 |
42 |
16 |
416 |
| Paclitaxel |
Trolox C |
12 |
4 |
61 |
10 |
408 |
| Vinburnine |
Trolox C |
18 |
4 |
53 |
24 |
406 |
| Ozagrel |
Paclitaxel |
22 |
7 |
47 |
20 |
405 |
| Cytisine |
Vancomycin |
18 |
7 |
59 |
23 |
396 |
| Valproic acid | Trifluridine | 20 | 9 | 60 | 24 | 396 |
m1-the number of reversed genes by drug 1.
n1-the number of genes induced to the same deregulation as type 2 diabetes by drug 1.
M2-the number of reversed genes by drug 2.
n2-the number of genes induced to the same deregulation as type 2 diabetes by drug 2.