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. 2014 May 22;5(5):e1247. doi: 10.1038/cddis.2014.222

Figure 5.

Figure 5

SPAG5 regulation influenced mTOR signaling pathway activation in cervical cancer cell lines under taxol treatment. Taxol treatment after SPAG5 downregulation in (a) HeLa and (b) SiHa cervical cancer cell lines revealing differing drug sensitivities under different concentrations due to (c) apoptosis. (d) Western blot analysis of mTOR signaling pathway activation