Figure 5.

Expression of β-catenin rescued CRC cell malignant phenotypes that were suppressed by knockdown of Elf3. (a) The statistical analysis of CRC cell apoptosis in different experimental groups. The HCT116 and SW1116 cells were treated by specific siRNAs for Elf3 expression in the absence or presence of β-catenin expression vector. Statistical result based on three independent experiments (P-values indicated, t-test). (b, c) Representative flow cytometry images in experiments described above. (d, e) Statistical result and representative images of Transwell assay of HCT116 and SW116 cells treated by specific siRNAs for Elf3 expression in the absence or presence of β-catenin expression vector. (f, g) Proliferation of HCT116 and SW1116 cells treated by specific siRNAs for Elf3 expression in the absence or presence of β-catenin expression vector (P-values indicated, t-test)