Table 1. Blood cell counts from samples of Recql4HD and wild-type micea.
| Cell type | WT (mean±S.D.) | Recql4HD (mean±S.D.) | P-value |
|---|---|---|---|
| WBC (103/μl) | 7.70±1.06 | 4.13±0.43 | 0.0016 |
| RBC (107/μl) | 9.58±0.38 | 7.73±0.10 | 0.0016 |
| Platelet (103/μl) | 833.50±85.07 | 738.67±6.11 | 0.0558 |
| PMNs (103/μl) | 1.03±0.41 | 0.73±0.07 | 0.1162 |
| Lymphocytes (103/μl) | 6.42±0.79 | 3.32±0.37 | 0.0008 |
| Monocytes (103/μl) | 0.21±0.02 | 0.07±0.02 | 0.0004 |
| Eosinophils (102/μl) | 0.25±0.44 | 0.01±0.01 | 0.2741 |
| Basophils (102/μl) | 0.02±0.04 | 0.00±0.00 | 0.1866 |
Abbreviations: PMNs, polymorphonuclear leukocytes; RBC, red blood cells; S.D., standard deviation; WBC, white blood cell
a
Four wild-type mice and three Recql4 mutant Recql4HD mice at the age of 4 months were used in the experiment