Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 May 22;5(5):e1253. doi: 10.1038/cddis.2014.231

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Macmillan Publishers Limited

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

PMC Copyright notice

CDK1 phosphorylation is maintained in CHK1-depleted HCT116 cells during DNA replication stress. Western blot analysis of indicated S-phase regulatory proteins from extracts of HCT116 or HCT116 p53−/− cells pretreated with CHK1 or control siRNAs and exposed or not exposed to thymidine (2 mM, 24 h). β-Actin levels are presented as loading controls