Table 1. EC50 calculated after 72 h of treatment with UCN-01.
GSC no. | EC50 (μM) | Sensitivity |
---|---|---|
T98G | 0.003 | High |
12 | 0.043 | High |
15 | 0.090 | High |
5 | 0.094 | High |
14 | 0.184 | High |
13 | 0.221 | High |
10 | 0.242 | High |
11 | 0.367 | Medium |
18 | 0.414 | Medium |
7 | 0.548 | Medium |
4 | 0.581 | Medium |
6 | 0.628 | Medium |
8 | 0.805 | Medium |
9 | 0.949 | Medium |
1 | 1.436 | Low |
17 | 1.938 | Low |
U87MG | 2.711 | Low |
16 | 3.416 | Low |
3 | 4269.117 | Low |
20 | 79056.358 | Low |
2 | 227826.165 | Low |
19 | 341092.047 | Low |
Sensitivity range: high <250 nM; 250 nM < medium <1 μM; low >1 μM.
GSC lines are ordered by their sensitivity to UCN-01