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. 2014 May 15;5(5):e1227. doi: 10.1038/cddis.2014.186

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Copyright © 2014 Macmillan Publishers Limited

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

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Silencing of miR-374a inhibits migration and invasion in gefitinib-resistant NSCLC. (a and b) The representative images show the migration ability of Calu1 and HCC827-Gef cells with transfection of miRZip-374a or miRZip-control. (c and d) The invasive cells were stained and counted under the microscope. Quantitative results for the transmembrane ability of each group of cells. All data are given as mean ±S.D. of three independent experiments. Significant differences are indicated as follows: one-sample t-test, *P<0.05