Figure 7.

Inhibition of cellular viability by amorphous silica nanoparticles.

Notes: Inhibition of cellular viability by 50 nm (A) and 500 nm (B) amorphous silica nanoparticles. Exponentially growing human umbilical vein endothelial cells were treated with either saline or various concentrations (0.1–100 μg/mL) of 50 nm or 500 nm silica nanoparticles. Viable cells were assayed as described in materials and methods. All experiments were repeated three times. Data are mean ± standard error of mean. *P<0.001 compared with the corresponding control-treated group.

Abbreviations: HUVEC, human umbilical vein endothelial cells; SiNP, silica nanoparticle.